Moderate interactionModerate
Magnesium glycinate and Alcohol: interaction, severity and spacing
Magnesium glycinate and Alcohol interact because alcohol increases renal magnesium excretion and impairs absorption, worsening magnesium depletion; sedative effects also add. Take them with care. Moderate risk.
Last reviewed: 2026-09-20Reviewed by: StackingRight clinical review
The interaction in detail
| Pair | Magnesium glycinate and Alcohol |
|---|---|
| Type | Food interaction |
| Severity | Moderate |
| Required spacing | None specified |
| Onset | At the time of dosing |
Mechanism
Alcohol increases renal magnesium excretion and impairs absorption, worsening magnesium depletion; sedative effects also add.
What to do
Avoid taking magnesium with alcohol. Separate by several hours and do not use it to offset drinking.
How to fit both into one day
Magnesium glycinate
eveningflexible
Magnesium supports parasympathetic tone and muscle relaxation, so evening dosing also helps sleep. Keep it two hours from antibiotics and thyroid medication.
Putting Magnesium glycinate in the evening and Alcohol in the evening satisfies the 0-hour separation without disrupting either one's absorption window.