Other compound

CoQ10

CoQ10 has no established recommended dietary allowance. It works best alongside CoQ10 (ubiquinol).

Last reviewed: 2026-09-20Reviewed by: StackingRight clinical reviewPrimary source

What CoQ10 does

Electron carrier in mitochondrial respiration and a lipid-phase antioxidant.

No RDA established. Ubiquinol is the reduced, better-absorbed form. Fat-soluble.

How much you need

Reference intakes for CoQ10 in adults
MeasureAdult maleAdult female
Recommended intakeNot establishedNot established
Upper intake levelNone established
Typical supplement dose100-200 mg

Interactions involving CoQ10

2 sourced rules
Interaction rules involving CoQ10
PairSeverityMechanismAction
CoQ10 (ubiquinol) × Vitamin E (mixed tocopherols)MildBoth are lipid-phase antioxidants that use the same chylomicron absorption route, so they compete slightly for the same uptake capacity.No separation needed. Taking them together with fat is acceptable and common in cardiac formulas.Source
CoQ10 (ubiquinol) × Avocado / olive oilSynergyCoQ10 is highly lipophilic; absorption rises several-fold when taken with a fat-containing meal.Take CoQ10 with the fattiest meal of your day. Splitting the dose further improves uptake.Source

Questions people ask about CoQ10

Sources