What does Quercetin interact with?

Quercetin interacts with Statin at a mild level. The most significant pairing on record involves Statin: Keep the quercetin dose consistent; report muscle aches or weakness.

What happens if I take too much Quercetin?

No upper limit has been established, which reflects self-regulating absorption rather than unlimited safety.

Should I take Quercetin with food?

Quercetin does not have a strong food dependency, though taking it with a meal reduces stomach upset.

Other compound

Quercetin

Quercetin has no established recommended dietary allowance.

Last reviewed: 2026-09-20Reviewed by: StackingRight clinical reviewPrimary source

What Quercetin does

Flavonol with antihistamine and senolytic activity in vitro.

No RDA. Inhibits organic anion transporters, which can raise drug levels.

How much you need

Reference intakes for Quercetin in adults
Measure	Adult male	Adult female
Recommended intake	Not established	Not established
Upper intake level	None established
Typical supplement dose	500-1000 mg

Interactions involving Quercetin

1 sourced rule

Interaction rules involving Quercetin
Pair	Severity	Mechanism	Action
Quercetin × Statin	Mild	Quercetin inhibits organic anion transporting polypeptide (OATP) transporters, which can modestly raise statin blood levels.	Keep the quercetin dose consistent; report muscle aches or weakness.Source

Questions people ask about Quercetin

Sources

https://pubmed.ncbi.nlm.nih.gov/23351939/